Phospho-GCN2-T899 Polyclonal Antibody
- SKU:
- CABP1428
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | Phospho-GCN2-T899 Polyclonal Antibody |
| Product Code: | CABP1428 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa |
| Cellular Location: | cytosol, cytosolic ribosome |
This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2.
| Immunogen: | A synthetic phosphorylated peptide around T899 of human Phospho-GCN2-T899. |
| Sequence: | HLTGM |
| Synonyms: | GCN2, PVOD2 |
| Calculated MW: | 187kDa |
| Observed MW: | 187kDa |
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