Phospho-GCN2-T899 Monoclonal Antibody

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SKU:
CABP1356
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB

Description

Product Name:Phospho-GCN2-T899 Monoclonal Antibody
Product Code:CABP1356
Reactivity:Human
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC57177
Reactivity:Human
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:1000-1:5000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:HeLa+Calyculin A
Cellular Location:Cytosol, Cytosolic ribosome

This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2.

Immunogen:A synthetic phosphorylated peptide around T899 of human Phospho-GCN2-T899 (NP_001013725.2).
Sequence:HLTGM
Synonyms:GCN2, PVOD2
Calculated MW:187kDa
Observed MW:220kDa
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