Phospho-ERF (T526) Antibody (PACO03638)
- SKU:
- PACO03638
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | Phospho-ERF (T526) Antibody |
| Antibody SKU: | PACO03638 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | synthesized peptide derived from human ERF around the phosphorylation site of T526. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | ERF; ETS domain-containing transcription factor ERF; Ets2 repressor factor; PE-2 |
| UniProt Protein Function: | ERF: potent transcriptional repressor that binds to the H1 element of the ETS2 promoter. Belongs to the ETS family of transcription factors. Its function is regulated by phosphorylation. |
| UniProt Protein Details: | Protein type:DNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 19q13 Cellular Component: cytosol; Golgi apparatus; nucleoplasm; nucleus Molecular Function:sequence-specific DNA binding; transcription corepressor activity Biological Process: cell cycle; cell differentiation; negative regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent Disease: Craniosynostosis 4 |
| NCBI Summary: | ETS2 is a transcription factor and protooncogene involved in development, apoptosis, and the regulation of telomerase. The protein encoded by this gene binds to the ETS2 promoter and is a strong repressor of ETS2 transcription. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Aug 2015] |
| UniProt Code: | P50548 |
| NCBI GenInfo Identifier: | 50403684 |
| NCBI Gene ID: | 2077 |
| NCBI Accession: | P50548.2 |
| UniProt Secondary Accession: | P50548,Q59G38, Q9UPI7, B2RAP1, B7Z4R0, |
| UniProt Related Accession: | P50548 |
| Molecular Weight: | 49,965 Da |
| NCBI Full Name: | ETS domain-containing transcription factor ERF |
| NCBI Synonym Full Names: | ETS2 repressor factor |
| NCBI Official Symbol: | ERF |
| NCBI Official Synonym Symbols: | PE2; CRS4; PE-2 |
| NCBI Protein Information: | ETS domain-containing transcription factor ERF |
| UniProt Protein Name: | ETS domain-containing transcription factor ERF |
| UniProt Synonym Protein Names: | Ets2 repressor factor; PE-2 |
| Protein Family: | Essential recombination function protein |
| UniProt Gene Name: | ERF |
| UniProt Entry Name: | ERF_HUMAN |
