Phospho-eIF4EBP1-T37/T46 Monoclonal Antibody

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SKU:
CABP1381
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB

Description

Product Name:Phospho-eIF4EBP1-T37/T46 Monoclonal Antibody
Product Code:CABP1381
Reactivity:Rat
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC56491
Reactivity:Rat
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:2000-1:8000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:C6

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Immunogen:A synthetic phosphorylated peptide around T37&T46 of human EIF4EBP1.
Sequence:Email for sequence
Synonyms:BP-1, 4EBP1, 4E-BP1, PHAS-I
Calculated MW:13kDa
Observed MW:15-20kDa
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