Phospho-eIF4E-S209 Rabbit mAb
- SKU:
- CABP1024
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Applications:
- WB
- Isotype:
- IgG
- Host Species:
- Rabbit
Description
| Product Name: | Phospho-eIF4E-S209 Rabbit mAb |
| Product Code: | CABP1024 |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: |
| Applications: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | HeLa |
| Immunogen: | |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | |
| Gene ID: | 1977 |
| Cellular Location: | |
| Calculated MW: | 25kDa |
| Observed MW: | 25KDa |
| Synonyms: | AUTS19, CBP, EIF4E1, EIF4EL1, EIF4F, eIF-4E |
| Uniprot: | P06730 |
| Background: | The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] |
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