Phospho-Cytokeratin 8 (KRT8)-S74 Polyclonal Antibody (CABP1299)
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- SKU:
- CABP1299
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | Phospho-Cytokeratin 8 (KRT8)-S74 Polyclonal Antibody |
| Product Code: | CABP1299 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | Hep G2 |
| Cellular Location: | Cytoplasm, Nucleus, Nucleus matrix, nucleoplasm |
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.
| Immunogen: | A synthetic phosphorylated peptide around S74 of human Cytokeratin 8 (NP_002264.1). |
| Sequence: | LLSPL |
| Synonyms: | K8, KO, CK8, CK-8, CYK8, K2C8, CARD2 |
| Calculated MW: | 54kDa |
| Observed MW: | 60kDa |
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