Phospho-Camk2-T286 Monoclonal Antibody

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SKU:
CABP1386
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB

Description

Product Name:Phospho-Camk2-T286 Monoclonal Antibody
Product Code:CABP1386
Reactivity:Mouse, Rat
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC57709
Reactivity:Mouse, Rat
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:2000-1:10000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:Mouse brain
Cellular Location:Cell junction, Presynaptic cell membrane, Synapse
Customer Validation:WB(Mus musculus, Homo sapiens)

The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2 )/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Several transcript variants encoding distinct isoforms have been identified for this gene.

Immunogen:A synthetic phosphorylated peptide around T286 of human Camk2.
Sequence:QETVD
Synonyms:CAMKA, MRD53, MRT63, CaMKIIalpha, CaMKIINalpha, CAM2, CAMK2, CAMKB, MRD54, CaMKIIbeta, CAMKD, CAMK, CAMKG, MRD59, CAMK-II
Calculated MW:54kDa
Observed MW:50kDa
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