Phospho-Camk2-T286 Monoclonal Antibody
- SKU:
- CABP1386
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | Phospho-Camk2-T286 Monoclonal Antibody |
| Product Code: | CABP1386 |
| Reactivity: | Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC57709 |
| Reactivity: | Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:2000-1:10000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Mouse brain |
| Cellular Location: | Cell junction, Presynaptic cell membrane, Synapse |
| Customer Validation: | WB(Mus musculus, Homo sapiens) |
The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2 )/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Several transcript variants encoding distinct isoforms have been identified for this gene.
| Immunogen: | A synthetic phosphorylated peptide around T286 of human Camk2. |
| Sequence: | QETVD |
| Synonyms: | CAMKA, MRD53, MRT63, CaMKIIalpha, CaMKIINalpha, CAM2, CAMK2, CAMKB, MRD54, CaMKIIbeta, CAMKD, CAMK, CAMKG, MRD59, CAMK-II |
| Calculated MW: | 54kDa |
| Observed MW: | 50kDa |
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