Phospho-ADD1/ADD2 (S726/713) Antibody (PACO00316)
- SKU:
- PACO00316
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | Phospho-ADD1/ADD2 (S726/713) Antibody |
| Antibody SKU: | PACO00316 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | synthesized peptide derived from human Adducin alpha/Beta around the phosphorylation site of S726/713. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | ADD1; ADDA; Alpha-adducin; Erythrocyte adducin subunit alpha; ADD2; ADDB; Beta-adducin; Erythrocyte adducin subunit beta |
| UniProt Protein Function: | Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin. |
| NCBI Summary: | Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, and gamma). Adducin acts as a heterodimer of the related alpha, beta, or gamma subunits. The protein encoded by this gene represents the alpha subunit. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. [provided by RefSeq, Aug 2017] |
| UniProt Code: | P35611 |
| NCBI GenInfo Identifier: | 12644231 |
| NCBI Gene ID: | 118 |
| NCBI Accession: | P35611.2 |
| UniProt Secondary Accession: | P35611,Q13734, Q14729, Q16156, Q86XM2, Q9UJB6, A2A3N8 A2A3P0, B4DI79, D3DVR3, D3DVR4, D3DVR5, |
| UniProt Related Accession: | P35611 |
| Molecular Weight: | 73,333 Da |
| NCBI Full Name: | Alpha-adducin |
| NCBI Synonym Full Names: | adducin 1 |
| NCBI Official Symbol: | ADD1 |
| NCBI Official Synonym Symbols: | ADDA |
| NCBI Protein Information: | alpha-adducin |
| UniProt Protein Name: | Alpha-adducin |
| UniProt Synonym Protein Names: | Erythrocyte adducin subunit alpha |
| Protein Family: | Alpha-adducin |
| UniProt Gene Name: | ADD1 |
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