PHLDA1 Antibody (PACO55230)
- SKU:
- PACO55230
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | PHLDA1 Antibody (PACO55230) |
| Antibody SKU: | PACO55230 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Pleckstrin homology-like domain family A member 1 protein (1-138AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human liver tissue using PACO55230 at dilution of 1: 100. |
 | Immunofluorescence staining of HepG2 cells with PACO55230 at 1: 133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized tissue using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C.The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Seems to be involved in regulation of apoptosis. May be involved in detachment-mediated programmed cell death. May mediate apoptosis during neuronal development. May be involved in regulation of anti-apoptotic effects of IGF1. May be involved in translational regulation. |
| Synonyms: | Pleckstrin homology-like domain family A member 1 (Apoptosis-associated nuclear protein) (Proline- and glutamine-rich protein) (PQ-rich protein) (PQR protein) (Proline- and histidine-rich protein) (T-cell death-associated gene 51 protein), PHLDA1, PHRIP TDAG51 |
| UniProt Protein Function: | PHLDA1: Seems to be involved in regulation of apoptosis. May be involved in detachment-mediated programmed cell death. May mediate apoptosis during neuronal development. May be involved in regulation of anti-apoptotic effects of IGF1. May be involved in translational regulation.Protein type: Nucleolus; ApoptosisChromosomal Location of Human Ortholog: 12q15Cellular Component: cytosolMolecular Function: protein bindingBiological Process: G2/M transition of mitotic cell cycle |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes an evolutionarily conserved proline-histidine rich nuclear protein. The encoded protein may play an important role in the anti-apoptotic effects of insulin-like growth factor-1. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8WV24 |
| NCBI GenInfo Identifier: | 229463035 |
| NCBI Gene ID: | 22822 |
| NCBI Accession: | Q8WV24.4 |
| UniProt Secondary Accession: | Q8WV24,Q15184, Q2TAN2, Q9NZ17, A1A4G9 |
| UniProt Related Accession: | Q8WV24 |
| Molecular Weight: | 45,016 Da |
| NCBI Full Name: | Pleckstrin homology-like domain family A member 1 |
| NCBI Synonym Full Names: | pleckstrin homology like domain family A member 1 |
| NCBI Official Symbol: | PHLDA1 |
| NCBI Official Synonym Symbols: | PHRIP; TDAG51; DT1P1B11 |
| NCBI Protein Information: | pleckstrin homology-like domain family A member 1 |
| UniProt Protein Name: | Pleckstrin homology-like domain family A member 1 |
| UniProt Synonym Protein Names: | Apoptosis-associated nuclear protein; Proline- and glutamine-rich protein; PQ-rich protein; PQR protein; Proline- and histidine-rich protein; T-cell death-associated gene 51 protein |
| Protein Family: | Pleckstrin homology-like domain family |
| UniProt Gene Name: | PHLDA1 |
| UniProt Entry Name: | PHLA1_HUMAN |
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