PHD3 Monoclonal Antibody
- SKU:
- CAB21225
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
Description
| Product Name: | PHD3 Monoclonal Antibody |
| Product Code: | CAB21225 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC52452 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Recommended Dilution: | WB 1:10000, -20000, IHC-P 1:500-1:1000, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | BxPC-3, Mouse kidney, Mouse brain |
| Cellular Location: | Cytoplasm, Nucleus |
Enables peptidyl-proline 4-dioxygenase activity. Involved in several processes, including activation of cysteine-type endopeptidase activity involved in apoptotic process; peptidyl-proline hydroxylation to 4-hydroxy-L-proline; and response to hypoxia. Located in cytosol and nucleus. Implicated in renal cell carcinoma. Biomarker of clear cell renal cell carcinoma.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PHD3 (NP_071356.1). |
| Sequence: | MPLGH IMRLD LEKIA LEYIV PCLHE VGFCY LDNFL GEVVG DCVLE RVKQL HCTGA LRDGQ LAGPR AGVSK RHLRG DQITW IGGNE EGCEA ISFLL SLIDR |
| Synonyms: | PHD3, HIFPH3, HIFP4H3 |
| Calculated MW: | 27kDa |
| Observed MW: | 32kDa |
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