Description
Antibody Name: | PGP Antibody (PACO46106) |
Antibody SKU: | PACO46106 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Glycerol-3-phosphate phosphatase protein (140-300AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human tonsil tissue using PACO46106 at dilution of 1:100. |
![]() | Immunofluorescent analysis of MCF-7 cells using PACO46106 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
Background: | Glycerol-3-phosphate phosphatase hydrolyzing glycerol-3-phosphate into glycerol. Thereby, regulates the cellular levels of glycerol-3-phosphate a metabolic intermediate of glucose, lipid and energy metabolism. Was also shown to have a 2-phosphoglycolate phosphatase activity and a tyrosine-protein phosphatase activity. However, their physiological relevance is unclear. In vitro, has also a phosphatase activity toward ADP, ATP, GDP and GTP (By similarity). |
Synonyms: | Glycerol-3-phosphate phosphatase (G3PP) (EC 3.1.3.21) (Aspartate-based ubiquitous Mg(2+)-dependent phosphatase) (AUM) (EC 3.1.3.48) (Phosphoglycolate phosphatase) (PGP), PGP |
UniProt Protein Function: | PGP: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. |
UniProt Protein Details: | Protein type:Carbohydrate Metabolism - glyoxylate and dicarboxylate; EC 3.1.3.48; EC 3.1.3.18; Phosphatase (non-protein) Chromosomal Location of Human Ortholog: 16p13.3 Molecular Function:phosphoglycolate phosphatase activity; magnesium ion binding; protein tyrosine phosphatase activity Biological Process: dephosphorylation; carbohydrate metabolic process |
UniProt Code: | A6NDG6 |
NCBI GenInfo Identifier: | 166987826 |
NCBI Gene ID: | 283871 |
NCBI Accession: | A6NDG6.1 |
UniProt Related Accession: | A6NDG6 |
Molecular Weight: | 34,006 Da |
NCBI Full Name: | Phosphoglycolate phosphatase |
NCBI Synonym Full Names: | phosphoglycolate phosphatase |
NCBI Official Symbol: | PGP |
NCBI Protein Information: | phosphoglycolate phosphatase; PGPase |
UniProt Protein Name: | Phosphoglycolate phosphatase |
Protein Family: | Glycerol-3-phosphate phosphatase |
UniProt Gene Name: | PGP |
UniProt Entry Name: | PGP_HUMAN |