PGLYRP4 Antibody (PACO28902)
- SKU:
- PACO28902
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | PGLYRP4 Antibody (PACO28902) |
| Antibody SKU: | PACO28902 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Peptidoglycan recognition protein 4 protein (18-317AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human skin tissue using PACO28902 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human gastric cancer using PACO28902 at dilution of 1:100. |
| Background: | Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity. |
| Synonyms: | Peptidoglycan recognition protein 4 (Peptidoglycan recognition protein I-beta) (PGLYRPIbeta) (PGRP-I-beta) (Peptidoglycan recognition protein intermediate beta), PGLYRP4, PGRPIB |
| UniProt Protein Function: | PGLYRP4: Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 1q21Molecular Function: peptidoglycan binding; peptidoglycan receptor activityBiological Process: defense response to Gram-positive bacterium; detection of bacterium |
| UniProt Protein Details: | |
| NCBI Summary: | Summary: This gene encodes a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. These proteins are part of the innate immune system and recognize peptidoglycan, a ubiquitous component of bacterial cell walls. This antimicrobial protein binds to murein peptidoglycans of Gram-positive bacteria. [provided by RefSeq, Oct 2014] |
| UniProt Code: | Q96LB8 |
| NCBI GenInfo Identifier: | 143811439 |
| NCBI Gene ID: | 57115 |
| NCBI Accession: | Q96LB8.2 |
| UniProt Secondary Accession: | Q96LB8,Q3B822, Q3B823, Q5SY63, Q5SY64, Q9HD75, A8K838 |
| UniProt Related Accession: | Q96LB8 |
| Molecular Weight: | |
| NCBI Full Name: | Peptidoglycan recognition protein 4 |
| NCBI Synonym Full Names: | peptidoglycan recognition protein 4 |
| NCBI Official Symbol: | PGLYRP4 |
| NCBI Official Synonym Symbols: | PGRPIB; SBBI67; PGRP-Ibeta; PGLYRPIbeta |
| NCBI Protein Information: | peptidoglycan recognition protein 4 |
| UniProt Protein Name: | Peptidoglycan recognition protein 4 |
| UniProt Synonym Protein Names: | Peptidoglycan recognition protein I-beta; PGLYRPIbeta; PGRP-I-beta; Peptidoglycan recognition protein intermediate beta |
| Protein Family: | Peptidoglycan recognition protein |
| UniProt Gene Name: | PGLYRP4 |
| UniProt Entry Name: | PGRP4_HUMAN |
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