PGLYRP3 Antibody (PACO58841)
- SKU:
- PACO58841
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | PGLYRP3 Antibody (PACO58841) |
| Antibody SKU: | PACO58841 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Peptidoglycan recognition protein 3 protein (90-222AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: MCF-7 whole cell lysate, Colo320 whole cell lysate. All lanes: PGLYRP3 antibody at 4.86µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 38 kDa. Observed band size: 38 kDa. |
| Background: | Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity. |
| Synonyms: | Peptidoglycan recognition protein 3 (Peptidoglycan recognition protein I-alpha) (PGLYRPIalpha) (PGRP-I-alpha) (Peptidoglycan recognition protein intermediate alpha), PGLYRP3, PGRPIA |
| UniProt Protein Function: | PGLYRP3: Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.Protein type: Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 1q21Molecular Function: peptidoglycan binding; peptidoglycan receptor activityBiological Process: defense response to Gram-positive bacterium; detection of bacterium |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. These proteins are part of the innate immune system and recognize peptidoglycan, a ubiquitous component of bacterial cell walls. This antimicrobial protein binds to murein peptidoglycans of Gram-positive bacteria. [provided by RefSeq, Oct 2014] |
| UniProt Code: | Q96LB9 |
| NCBI GenInfo Identifier: | 16418405 |
| NCBI Gene ID: | |
| NCBI Accession: | NP_443123.1 |
| UniProt Secondary Accession: | Q96LB9,Q5SY65, A1A4U8 |
| UniProt Related Accession: | Q96LB9 |
| Molecular Weight: | |
| NCBI Full Name: | |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | |
| UniProt Protein Name: | Peptidoglycan recognition protein 3 |
| UniProt Synonym Protein Names: | Peptidoglycan recognition protein I-alpha; PGLYRPIalpha; PGRP-I-alpha; Peptidoglycan recognition protein intermediate alpha |
| Protein Family: | |
| UniProt Gene Name: | PGLYRP3 |
| UniProt Entry Name: | PGRP3_HUMAN |
| Antibodies | ELISA Kits |
| PGLYRP3 Antibody (PACO11198) | Human Peptidoglycan recognition protein 3 (PGLYRP3) ELISA Kit |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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