PGAP2 Antibody (PACO48142)
- SKU:
- PACO48142
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | PGAP2 Antibody (PACO48142) |
| Antibody SKU: | PACO48142 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Post-GPI attachment to proteins factor 2 protein (45-114AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human brain tissue using PACO48142 at dilution of 1:100. |
 | Immunofluorescent analysis of MCF-7 cells using PACO48142 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
 | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO48142 at dilution of 1:100. |
| Background: | Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface (By similarity). |
| Synonyms: | Post-GPI attachment to proteins factor 2 (FGF receptor-activating protein 1), PGAP2, FRAG1 |
| UniProt Protein Function: | PGAP2: Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface. Belongs to the PGAP2 family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 11p15.5Cellular Component: Golgi membrane; endoplasmic reticulum membrane; integral to membrane; nucleusMolecular Function: protein transporter activityBiological Process: protein transport; DNA damage response, signal transduction; GPI anchor biosynthetic process; DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9UHJ9 |
| NCBI GenInfo Identifier: | 224177563 |
| NCBI Gene ID: | 27315 |
| NCBI Accession: | NP_001138910.1 |
| UniProt Secondary Accession: | Q9UHJ9,Q6UC77, Q96G66, Q9UF01, Q9Y4N1, E9PJG5, H7BXL9 |
| UniProt Related Accession: | Q9UHJ9 |
| Molecular Weight: | 29400 |
| NCBI Full Name: | post-GPI attachment to proteins factor 2 isoform 2 |
| NCBI Synonym Full Names: | post-GPI attachment to proteins 2 |
| NCBI Official Symbol: | PGAP2 |
| NCBI Official Synonym Symbols: | FRAG1; MRT17; MRT21; HPMRS3; CWH43-N |
| NCBI Protein Information: | post-GPI attachment to proteins factor 2 |
| UniProt Protein Name: | Post-GPI attachment to proteins factor 2 |
| UniProt Synonym Protein Names: | FGF receptor-activating protein 1 |
| Protein Family: | PGAP2-interacting protein |
| UniProt Gene Name: | PGAP2 |
| UniProt Entry Name: | PGAP2_HUMAN |
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