PFKFB1 Polyclonal Antibody
- SKU:
- CAB10654
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | PFKFB1 Polyclonal Antibody |
| Product Code: | CAB10654 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2, 6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2, 6-biphosphate using independent catalytic domains. Fructose-2, 6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2, 6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 252-471 of human PFKFB1 (NP_002616.2). |
| Sequence: | RSIYL CRHGE SELNI RGRIG GDSGL SVRGK QYAYA LANFI QSQGI SSLKV WTSHM KRTIQ TAEAL GVPYE QWKAL NEIDA GVCEE MTYEE IQEHY PEEFA LRDQD KYRYR YPKGE SYEDL VQRLE PVIME LERQE NVLVI CHQAV MRCLL AYFLD KSSDE LPYLK CPLHT VLKLT PVAYG CKVES IYLNV EAVNT HREKP ENVDI TREPE EALDT VPAHY |
| Synonyms: | F6PK, HL2K, PFRX |
| Calculated MW: | 55kDa |
| Observed MW: | Refer to figures |
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