Description
Product Name: | Peroxiredoxin 5 (PRDX5) Monoclonal Antibody |
Product Code: | CAB24731 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunohistochemistry |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC59822 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IHC-P, ELISA |
Key Applications: | Western blotting, Immunohistochemistry |
Recommended Dilution: | WB 1:1000-1:5000, IHC-P 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | HeLa, 293T, Mouse kidney, Mouse liver, Rat kidney, Rat brain |
Cellular Location: | Cytoplasm, Mitochondrion, Peroxisome |
This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein interacts with peroxisome receptor 1 and plays an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. The use of alternate transcription start sites is thought to result in transcript variants that use different in-frame translational start codons to generate isoforms that are targeted to the mitochondrion (isoform L) or peroxisome/cytoplasm (isoform S). Multiple related pseudogenes have been defined for this gene.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to aminoacids 53-214 of human Peroxiredoxin 5 (PRDX5)(NP_036226.2). |
Sequence: | MAPIK VGDAI PAVEV FEGEP GNKVN LAELF KGKKG VLFGV PGAFT PGCSK THLPG FVEQA EALKA KGVQV VACLS VNDAF VTGEW GRAHK AEGKV RLLAD PTGAF GKETD LLLDD SLVSI FGNRR LKRFS MVVQD GIVKA LNVEP DGTGL TCSLA PNIIS QL |
Synonyms: | PLP, ACR1, B166, PRXV, PMP20, PRDX6, prx-V, SBBI10, AOEB166, HEL-S-55 |
Calculated MW: | 22kDa |
Observed MW: | 17kDa |