Perilipin-2 Polyclonal Antibody (CAB22016)
- SKU:
- CAB22016
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
Description
| Product Name: | Perilipin-2 Polyclonal Antibody |
| Product Code: | CAB22016 |
| Reactivity: | Human, Rat |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Rat |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:100-1:500, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | HuH-7 |
| Cellular Location: | cytosol, endoplasmic reticulum, extracellular region, lipid droplet, nucleus, plasma membrane |
The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 300-437 of human Perilipin-2 (NP_001113.2). |
| Sequence: | SHCAE HIESR TLAIA RNLTQ QLQTT CHTLL SNIQG VPQNI QDQAK HMGVM AGDIY SVFRN AASFK EVSDS LLTSS KGQLQ KMKES LDDVM DYLVN NTPLN WLVGP FYPQL TESQN AQDQG AEMDK SSQET QRSEH KTH |
| Synonyms: | ADFP, ADRP |
| Calculated MW: | 48kDa |
| Observed MW: | 48kDa |
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