Perilipin-2 Monoclonal Antibody (CAB22456)
- SKU:
- CAB22456
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
Description
| Product Name: | Perilipin-2 Monoclonal Antibody |
| Product Code: | CAB22456 |
| Reactivity: | Human, Mouse |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC51735 |
| Reactivity: | Human, Mouse |
| Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:500-1:1000, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HepG2 |
| Cellular Location: | Membrane, Peripheral membrane protein |
The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 88-437 of human Perilipin-2 (NP_001113.2). |
| Sequence: | DRIEE RLPIL NQPST QIVAN AKGAV TGAKD AVTTT VTGAK DSVAS TITGV MDKTK GAVTG SVEKT KSVVS GSINT VLGSR MMQLV SSGVE NALTK SELLV EQYLP LTEEE LEKEA KKVEG FDLVQ KPSYY VRLGS LSTKL HSRAY QQALS RVKEA KQKSQ QTISQ LHSTV HLIEF ARKNV YSANQ KIQDA QDKLY LSWVE WKRSI GYDDT DESHC AEHIE SRTLA IARNL TQQLQ TTCHT LLSNI QGVPQ NIQDQ AKHMG VMAGD IYSVF RNAAS FKEVS DSLLT SSKGQ LQKMK ESLDD VMDYL VNNTP LNWLV GPFYP QLTES QNAQD QGAEM DKSSQ ETQRS EHKTH |
| Synonyms: | ADFP, ADRP |
| Calculated MW: | 48kDa |
| Observed MW: | 52kDa |
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