PerCP/Cyanine5.5 Anti-Human CD14 Antibody [M5E2]
- SKU:
- AGEL2387
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Applications:
- FCM
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- Mouse IgG2a, κ
- Clone:
- M5E2
- Conjugation:
- PerCP/Cyanine5.5
Description
| Product Name: | PerCP/Cyanine5.5 Anti-Human CD14 Antibody [M5E2] |
| Product Code: | AGEL2387 |
| Clone No: | M5E2 |
| Synonyms: | Monocyte differentiation antigen CD14,CD14,Myeloid cell-specific leucine-rich glycoprotein |
| Reactivity: | Human |
| Host Species: | Mouse |
| Applications: | FCM |
| Isotype: | Mouse IgG2a, κ |
| Isotype Control: | PerCP/Cyanine5.5 Mouse IgG2a, κ Isotype Control [C1.18.4] (AGEL2578) |
| Conjugation: | PerCP/Cyanine5.5 |
| Form: | Liquid |
| Fluorescent Label: | PerCP/Cyanine5.5 is designed to be excited by the blue laser (488 nm) and detected using an optical filter centered near 675 nm (e.g., a 690/50 nm bandpass filter). |
| Recommended Use: | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
| Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Swissprot: | P08571 |
| Stability & Storage: | Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
| Shipping: | Biological ice pack at 4°C |
CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed at high levels on monocytes and macrophages, and at lower levels on granulocytes. Some dendritic cell populations such as interfollicular dendritic cells, reticular dendritic cells, and Langerhans cells have also been reported to express CD14. As a high-affinity receptor for LPS, CD14 is involved in the clearance of gram-negative pathogens, and in the upregulation of adhesion molecules and expression of cytokines in monocytes and neutrophils.
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