PE/GenieFluor 594 Anti-Mouse CD107a Antibody [1D4B]

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SKU:
AGEL3295
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Applications:
ICFCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, k
Clone:
1D4B
Conjugation:
PE/AF594

Description

Product Name:PE/AF594 Anti-Mouse CD107a Antibody [1D4B]
Product Code:AGEL3295
Size:50 Tests, 100 Tests, 200 Tests
Clone No:1D4B
Synonyms:LAMP-1, Lysosome-associated membrane glycoprotein 1, lysosomal membrane glycoprotein 1, CD107 antigen-like family member A, lysosome-associated membrane protein 1
Reactivity:Mouse
Host Species:Rat
Applications:FCM/ICFCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/GenieFluor 594 Rat IgG2a, κ Isotype Control [2A3] (AGEL3469)
Conjugation:PE/AF594
Applications:FCM/ICFCM
Recommended Dilution:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage:Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Fluorescent Label:PE/GenieFluor 594 is designed to be excited by the blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 620 nm (e.g., a 610/20 nm bandpass filter).
Shipping:Biological ice pack at 4°C
Form:Liquid
Gene ID:16783
Swissprot:P11438
Background Information:The 1D4B antibody recognizes CD107a which is also known as, Lysosome-Associated Membrane Protein 1 (LAMP-1). CD107a is one of the two major glycoproteins in lysosome membranes that provide useful markers to distinguish lysosomes from other organelles. CD107a may play a role in the lysosomal degradation of certain molecules. Mouse CD107a is a type I transmembrane glycoprotein. It consists of a 40-kDa core protein which is heavily glycosylated to form heterogeneous mature glycoprotein of 110-140 kDa. It is principally expressed in epithelial cells and macrophages in a variety of organs. Following activation, CD107a is relocated to the surface of some lymphocytes, macrophages, epithelial cells, endothelial cells, platelets, and tumor cells. Cell-surface CD107a may participate in intercellular adhesion and adhesion to the extracellular matrix. Cell surface CD107a expression can serve as a useful marker for cytotoxic NK and CD8+ T cells, as well as, some malignant tumor cells.
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