PE/GenieFluor 594 Anti-Human IL-4 Antibody [MP4-25D2]

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SKU:
AGEL3080
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
ICFCM
Reactivity:
Human
Host Species:
Rat
Isotype:
Rat IgG1, κ
Clone:
MP4-25D2
Conjugation:
PE/AF594

Description

Product Name:PE/GenieFluor 594 Anti-Human IL-4 Antibody [MP4-25D2]
Product Code:AGEL3080
Clone No:MP4-25D2
Synonyms:Interleukin-4,IL-4,B-cell IgG differentiation factor,B-cell growth factor 1,BSF-1,IGG1 induction factor
Reactivity:Human
Host Species:Rat
Applications:ICFCM
Isotype:Rat IgG1, κ
Isotype Control:PE/GenieFluor 594 Rat IgG2a, κ Isotype Control [2A3] (AGEL3469)
Conjugation:PE/AF594
Form:Liquid
Fluorescent Label:PE/AF594 is designed to be excited by the blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 620 nm (e.g., a 610/20 nm bandpass filter).
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Gene ID:3565
Swissprot:P05112
Stability & Storage:Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Shipping:Biological ice pack at 4°C

IL-4 is a pleiotropic cytokine that is produced by activated T cells, mast cells, and basophils. IL-4 elicits many different biological responses but has two dominant functions. The first is regulating differentiation of naïve CD4+ T cell to the Th2 type. Th2 cells produce IL-4, IL-5, IL-10, and IL-13, which tend to favor a humoral immune response while suppressing a cell-mediated immune response controlled by Th1 cells. The second is regulating IgE and IgG1 production by B cells.

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