Description
| Product Name: | PE/AF594 Anti-Human CD45RA Antibody [HI100] |
| Product Code: | AGEL3211 |
| Size: | 20 Tests, 100 Tests, 200 Tests |
| Clone No: | HI100 |
| Synonyms: | Receptor-type tyrosine-protein phosphatase C, Ptprc, L-CA, Ly-5, T200, CD45 |
| Reactivity: | Human |
| Host Species: | Mouse |
| Applications: | FCM |
| Isotype: | Mouse IgG2b, κ |
| Isotype Control: | PE/GenieFluor 594 Mouse IgG2b, κ Isotype Control [MPC-11] (AGEL3465) |
| Conjugation: | PE/AF594 |
| Applications: | FCM |
| Recommended Dilution: | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
| Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Storage: | Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
| Fluorescent Label: | PE/GenieFluor 594 is designed to be excited by the blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 620 nm (e.g., a 610/20 nm bandpass filter). |
| Shipping: | Biological ice pack at 4°C |
| Form: | Liquid |
| Gene ID: | 5788 |
| Swissprot: | P08575 |
| Background Information: | CD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphatase CD45. The CD45RA isoform is expressed on resting/naïve T cells, medullary thymocytes, B cells and monocytes. CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines. |
](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/590x590/products/11099/15153/human-cd45ra-monoclonal-antibody-pe-conjugated-hi100agel0230__49901__57751.1706269352.jpg?c=1 "Human CD45RA Monoclonal Antibody (PE Conjugated) [HI100](AGEL0230)")