PE/Cyanine7 Anti-Mouse CD38 Antibody [NIMR5] (AGEL2755)

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SKU:
AGEL2755
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, κ
Clone:
NIMR5
Conjugation:
PE/Cyanine7

Description

Product Name:PE/Cyanine7 Anti-Mouse CD38 Antibody [NIMR5] (AGEL2755)
Product Code:AGEL2755
Clone No:NIMR5
Synonyms:ADP-ribosyl cyclase 1,ADPRC 1,CD38,NIM-R5 antigen,2'-phospho-cyclic-ADP-ribose transferase
Reactivity:Mouse
Host Species:Rat
Applications:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Cyanine7 Rat IgG2a, κ Isotype Control [2A3] (AGEL2660)
Conjugation:PE/Cyanine7
Form:Liquid
Fluorescent Label:PE/Cyanine7 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 775 nm (e.g., a 780/60 nm bandpass filter).
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Swissprot:P56528
Stability & Storage:Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Shipping:Biological ice pack at 4°C

CD38 is a 42 kD glycoprotein, also known as T10. It is an ADP-ribosyl hydrolase, expressed on B cells, NK cells, a subset of T cells, brain, muscle, and kidney. In mouse, CD38 expression is downregulated on germinal center B cells and plasma cells, whereas this is not the case for humans. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, as well as adhesion and metabolism of cADPR and NAADP. CD31 is the ligand of CD38.

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