PE Anti-Human/Mouse IL-5 Antibody [TRFK5] (AGEL3282)
- SKU:
- AGEL3282
Description
| Product Name: | PE Anti-Human/Mouse IL-5 Antibody [TRFK5] |
| Product Code: | AGEL3282 |
| Size: | 25ug, 100ug |
| Clone No: | TRFK5 |
| Synonyms: | Interleukin-5, IL-5, B-cell differentiation factor I, T-cell replacing factor, TRF |
| Reactivity: | Human,Mouse |
| Host Species: | Rat |
| Applications: | ICFCM |
| Isotype: | Rat IgG1, κ |
| Isotype Control: | PE Rat IgG1, κ Isotype Control [HRPN] |
| Conjugation: | PE |
| Applications: | ICFCM |
| Recommended Dilution: | Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume]. |
| Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Storage: | Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
| Fluorescent Label: | PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter). |
| Shipping: | Biological ice pack at 4°C |
| Form: | Liquid |
| Swissprot: | P05113,P04401 |
| Background Information: | IL-5 is a homodimeric, disulphide-linked protein produced by T-cells. Monomeric human IL-5 is a 126 amino acid protein with a reported molecular weight of 26 kD for the homodimeric protein. Mouse and human IL-5 are approximately 70% identical. IL-5 has been shown to promote the growth of immature hematopoietic BFU-E progenitors, stimulate the activation and differentiation of eosinophils, and promote the generation of cytotoxic lymphocytes. Mouse IL-5 induces the differentiation and proliferation of pre-activated B-cells and stimulates the production and secretion of IgM and IgA by B-cells stimulated with bacterial endotoxin. The TRFK5 antibody can neutralize the bioactivity of natural or recombinant IL-5. |