PE Anti-Human CD7 Antibody [124-1D1]
- SKU:
- AGEL3040
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Applications:
- FCM
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- Mouse IgG1, κ
- Clone:
- 124-1D1
- Conjugation:
- PE
Description
| Product Name: | PE Anti-Human CD7 Antibody [124-1D1] |
| Product Code: | AGEL3040 |
| Clone No: | 124-1D1 |
| Synonyms: | T-cell antigen CD7,CD7,GP40,T-cell leukemia antigen,T-cell surface antigen Leu-9,TP41,TP41 |
| Reactivity: | Human |
| Host Species: | Mouse |
| Applications: | FCM |
| Isotype: | Mouse IgG1, κ |
| Isotype Control: | PE Mouse IgG1, κ Isotype Control [MOPC-21] (AGEL2550) |
| Conjugation: | PE |
| Form: | Liquid |
| Fluorescent Label: | PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter). |
| Recommended Use: | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
| Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Swissprot: | P09564 |
| Stability & Storage: | Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
| Shipping: | Biological ice pack at 4°C |
CD7 is a 40 kD type I transmembrane glycoprotein also known as gp40. It is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL) and some acute myeloid leukemia (AML) cells. CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 costimulation can induce cytokine secretion and modulate cellular adhesion.
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