PDZD2 Antibody (PACO23166)
- SKU:
- PACO23166
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | PDZD2 Antibody (PACO23166) |
| Antibody SKU: | PACO23166 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:50-1:100, IF:1:100-1:500 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthesized peptide derived from internal of human PDZD2. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry analysis of paraffin-embedded human prostate carcinoma tissue, using PDZD2 antibody. |
 | Immunofluorescence analysis of HepG2 cells, using PDZD2 antibody. |
| Background: | Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling. The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis. |
| Synonyms: | PDZ domain-containing protein 2; PDZ domain-containing protein 3; Activated in prostate cancer protein; Processed PDZ domain-containing protein 2; PDZD2 |
| UniProt Protein Function: | PDZD2: 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 5p13.3Cellular Component: endoplasmic reticulum; cytoplasm; extracellular region; intercellular junction; nucleusBiological Process: cell adhesion |
| UniProt Protein Details: | |
| NCBI Summary: | Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling. The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O15018 |
| NCBI GenInfo Identifier: | 87196343 |
| NCBI Gene ID: | 23037 |
| NCBI Accession: | NP_835260.2 |
| UniProt Secondary Accession: | O15018,Q9BXD4 |
| UniProt Related Accession: | O15018 |
| Molecular Weight: | 280,092 Da |
| NCBI Full Name: | PDZ domain-containing protein 2 |
| NCBI Synonym Full Names: | PDZ domain containing 2 |
| NCBI Official Symbol: | PDZD2 |
| NCBI Official Synonym Symbols: | AIPC; PIN1; PAPIN; PDZK3 |
| NCBI Protein Information: | PDZ domain-containing protein 2; PDZ domain-containing protein 3; activated in prostate cancer protein |
| UniProt Protein Name: | PDZ domain-containing protein 2 |
| UniProt Synonym Protein Names: | Activated in prostate cancer protein; PDZ domain-containing protein 3Cleaved into the following chain:Processed PDZ domain-containing protein 2 |
| Protein Family: | PDZ domain-containing protein |
| UniProt Gene Name: | PDZD2 |
| UniProt Entry Name: | PDZD2_HUMAN |
| Antibodies | ELISA Kits |
| PDZD2 Antibody (PACO03681) | Human PDZD2 (PDZ domain-containing protein 2) ELISA Kit (HUFI07281) |
| PDZD2 Antibody (PACO11156) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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