Description
| Product Name: | PDLIM5 Polyclonal Antibody |
| Product Code: | CAB22013 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:100-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa |
| Cellular Location: | actin cytoskeleton, cell projection, cytosol, postsynaptic density, presynapse, Z disc |
This gene encodes a member of a family of proteins that possess a 100-amino acid PDZ domain at the N terminus and one to three LIM domains at the C-terminus. This family member functions as a scaffold protein that tethers protein kinases to the Z-disk in striated muscles. It is thought to function in cardiomyocyte expansion and in restraining postsynaptic growth of excitatory synapses. Alternative splicing of this gene results in multiple transcript variants.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 300-400 of human PDLIM5 (NP_006448.5). |
| Sequence: | ADNTK KANNS QEPSP QLASS VASTR SMPES LDSPT SGRPG VTSLT AAAAF KPVGS TGVIK SPSWQ RPNQG VPSTG RISNS ATYSG SVAPA NSALG QTQPS D |
| Synonyms: | L9, ENH, LIM, ENH1 |
| Calculated MW: | 64kDa |
| Observed MW: | 64kDa |