pdeH Antibody (PACO63583)
- SKU:
- PACO63583
- Product Type:
- Antibody
- Reactivity:
- Bacteria - Escherichia coli
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | pdeH Antibody (PACO63583) |
| Antibody SKU: | PACO63583 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:2000-1:10000 |
| Species Reactivity: | Escherichia coli |
| Immunogen: | Recombinant Escherichia coli Cyclic di-GMP phosphodiesterase PdeH protein (1-255AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in Recombinant protein. All lanes: pdeH antibody at 1:2500. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 35 kDa. Observed band size: 34 kDa. |
| Background: | Involved in the control of the switch from cell motility to adhesion via regulation of cellular levels of cyclic-di-GMP (c-di-GMP). Part of a signaling cascade that regulates curli biosynthesis. The cascade is composed of two c-di-GMP control modules, in which c-di-GMP controlled by the DgcEPdeH pair (module I) regulates the activity of the DgcMPdeR pair (module II), which in turn regulates activity of the transcription factor MlrA and expression of the master biofilm regulator csgD. Effect on flagella is controlled via the c-di-GMP-binding flagellar brake protein YcgR. |
| Synonyms: | Cyclic di-GMP phosphodiesterase PdeH, pdeH, yhjH |
| UniProt Protein Function: | Involved in the control of the switch from cell motility to adhesion via regulation of cellular levels of cyclic-di-GMP (c-di-GMP) (PubMed:18765794). Part of a signaling cascade that regulates curli biosynthesis. The cascade is composed of two c-di-GMP control modules, in which c-di-GMP controlled by the DgcE/PdeH pair (module I) regulates the activity of the DgcM/PdeR pair (module II), which in turn regulates activity of the transcription factor MlrA and expression of the master biofilm regulator csgD (PubMed:23708798). Effect on flagella is controlled via the c-di-GMP-binding flagellar brake protein YcgR (PubMed:18765794). |
| UniProt Protein Details: | |
| NCBI Summary: | Overexpressed Salmonella typhimurium YhjH (STM3611) enhances motitility, counteracts cellulose biosynthesis and the rdar phenotype, and mediates cyclic-di-GMP degradation. [More information is available at EcoGene: EG12252]. YhjH is a c-di-GMP phosphodiesterase involved in regulation of the switch from flagellar motility to sessile behavior and curli expression at the end of exponential growth . [More information is available at EcoCyc: EG12252]. |
| UniProt Code: | P37646 |
| NCBI GenInfo Identifier: | 90111605 |
| NCBI Gene ID: | 948042 |
| NCBI Accession: | NP_417982.2 |
| UniProt Secondary Accession: | P37646,Q2M7I7 |
| UniProt Related Accession: | P37646 |
| Molecular Weight: | 29,601 Da |
| NCBI Full Name: | cyclic-di-GMP phosphodiesterase, FlhDC-regulated |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | yhjH |
| NCBI Official Synonym Symbols: | ECK3510; JW3493 |
| NCBI Protein Information: | cyclic-di-GMP phosphodiesterase, FlhDC-regulated |
| UniProt Protein Name: | Cyclic di-GMP phosphodiesterase PdeH |
| UniProt Synonym Protein Names: | |
| Protein Family: | |
| UniProt Gene Name: | pdeH |
| UniProt Entry Name: |
Related Products
HS3ST3B1 Antibody
Overview Product Name:HS3ST3B1 AntibodyProduct Code:PACO64781Size:50µLTarget Names:HS3ST3B1Species Reactivity:Human<
hns Antibody
Overview Product Name:hns AntibodyProduct Code:PACO64777Size:50µLTarget Names:hnsSpecies Reactivity:Escherichia coli
Avpr1b Antibody
Overview Product Name:Avpr1b AntibodyProduct Code:PACO64609Size:50µLTarget Names:Avpr1bSpecies Reactivity:RatHos
SPEF2 Antibody
Overview Product Name:SPEF2 AntibodyProduct Code:PACO64977Size:50µLTarget Names:SPEF2Species Reactivity:HumanHos
ompF Antibody
Overview Product Name:ompF AntibodyProduct Code:PACO64865Size:50µLTarget Names:ompFSpecies Reactivity:Escherichia coli