PDE4B Polyclonal Antibody
- SKU:
- CAB23257
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | PDE4B Polyclonal Antibody |
| Product Code: | CAB23257 |
| Reactivity: | Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Positive Samples: | Mouse lung |
| Cellular Location: | centrosome, cytosol, dendritic spine, excitatory synapse, gamma-tubulin complex, nucleus, perinuclear region of cytoplasm, postsynaptic density, synaptic vesicle, Z disc |
This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 636-736 of human PDE4B (NP_002591.2). |
| Sequence: | PDAQD ILDTL EDNRN WYQSM IPQSP SPPLD EQNRD CQGLM EKFQF ELTLD EEDSE GPEKE GEGHS YFSST KTLCV IDPEN RDSLG ETDID IATED KSPVD T |
| Synonyms: | DPDE4, PDEIVB |
| Calculated MW: | 83kDa |
| Observed MW: | 90kDa |
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