PCK1 Monoclonal Antibody
- SKU:
- CAB22172
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | PCK1 Monoclonal Antibody |
| Product Code: | CAB22172 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC56074 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:1000-1:5000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Hep G2, Mouse kidney, Rat kidney |
| Cellular Location: | Cytoplasm |
This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 523-622 of human PCK1 (NP_002582.3). |
| Sequence: | GKFLW PGFGE NSRVL EWMFN RIDGK ASTKL TPIGY IPKED ALNLK GLGHI NMMEL FSISK EFWEK EVEDI EKYLE DQVNA DLPCE IEREI LALKQ RISQM |
| Synonyms: | PCKDC, PEPCK1, PEPCKC, PEPCK-C |
| Calculated MW: | 69kDa |
| Observed MW: | 69kDa |
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