PCDHGB3 Antibody (PACO11102)
- SKU:
- PACO11102
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | PCDHGB3 Antibody (PACO11102) |
| Antibody SKU: | PACO11102 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human |
| Immunogen: | Human PCDHGB3 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | protocadherin γ subfamily B, 3;PCDHGB3;PCDH-GAMMA-B3 ; |
| UniProt Protein Function: | PCDHGB3: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 5q31Cellular Component: integral to membrane; plasma membraneMolecular Function: calcium ion bindingBiological Process: homophilic cell adhesion |
| UniProt Protein Details: | |
| NCBI Summary: | This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9Y5G1 |
| NCBI GenInfo Identifier: | 734703988 |
| NCBI Gene ID: | 56102 |
| NCBI Accession: | NP_061747.2 |
| UniProt Secondary Accession: | Q9Y5G1,Q9Y5C7, A7E229 |
| UniProt Related Accession: | Q9Y5G1 |
| Molecular Weight: | 89,370 Da |
| NCBI Full Name: | protocadherin gamma-B3 isoform 1 |
| NCBI Synonym Full Names: | protocadherin gamma subfamily B, 3 |
| NCBI Official Symbol: | PCDHGB3 |
| NCBI Official Synonym Symbols: | PCDH-GAMMA-B3 |
| NCBI Protein Information: | protocadherin gamma-B3 |
| UniProt Protein Name: | Protocadherin gamma-B3 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Protocadherin |
| UniProt Gene Name: | PCDHGB3 |
| UniProt Entry Name: | PCDGF_HUMAN |
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