PCDHA3 Antibody (PACO11096)
- SKU:
- PACO11096
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | PCDHA3 Antibody (PACO11096) |
| Antibody SKU: | PACO11096 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | |
| Species Reactivity: | Human |
| Immunogen: | Human PCDHA3 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | protocadherin α 3;PCDHA3;MGC141669;PCDH-ALPHA3 ; |
| UniProt Protein Function: | PCDHA3: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain. 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 5q31Cellular Component: integral to plasma membraneBiological Process: cell adhesion; nervous system development |
| UniProt Protein Details: | |
| NCBI Summary: | This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9Y5H8 |
| NCBI GenInfo Identifier: | 13878429 |
| NCBI Gene ID: | 56145 |
| NCBI Accession: | Q9Y5H8.1 |
| UniProt Secondary Accession: | Q9Y5H8,O75286 |
| UniProt Related Accession: | Q9Y5H8 |
| Molecular Weight: | 89,057 Da |
| NCBI Full Name: | Protocadherin alpha-3 |
| NCBI Synonym Full Names: | protocadherin alpha 3 |
| NCBI Official Symbol: | PCDHA3 |
| NCBI Official Synonym Symbols: | PCDH-ALPHA3 |
| NCBI Protein Information: | protocadherin alpha-3 |
| UniProt Protein Name: | Protocadherin alpha-3 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Protocadherin |
| UniProt Gene Name: | PCDHA3 |
| UniProt Entry Name: | PCDA3_HUMAN |
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