PCDH11Y/PCDH11X Antibody (PACO05447)
- SKU:
- PACO05447
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | PCDH11Y/PCDH11X Antibody (PACO05447) |
| Antibody SKU: | PACO05447 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:20000, IHC:1:100-1:300, IF:1:200-1:1000 |
| Species Reactivity: | Human |
| Immunogen: | Synthesized peptide derived from the Internal region of human Protocadherin-11. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | PCDH11Y; PCDH11; PCDH22; PCDHY; Protocadherin-11 Y-linked; Protocadherin-11; Protocadherin on the Y chromosome; PCDH-Y; Protocadherin prostate cancer; Protocadherin-PC; Protocadherin-22; PCDH11X; KIAA1326; PCDH11; PCDHX; Protocadherin-11 X- |
| UniProt Protein Function: | PCDH11Y: Potential calcium-dependent cell-adhesion protein. A chromosomal aberration involving PCDH11Y is a cause of multiple congenital abnormalities, including severe bilateral vesicoureteral reflux (VUR) with ureterovesical junction defects. Translocation t(Y;3)(p11;p12) with ROBO2. 4 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: Yp11.2 |
| UniProt Protein Details: | |
| NCBI Summary: | This gene belongs to the protocadherin family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing seven cadherin repeats, a transmembrane domain, and a cytoplasmic tail that differs from those of the classical cadherins. This gene is located on the Y chromosome in a block of X/Y homology and is very closely related to its paralog on the X chromosome. The protein is thought to play a role in cell-cell recognition during development of the central nervous system. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013] |
| UniProt Code: | Q9BZA8 |
| NCBI GenInfo Identifier: | 74762719 |
| NCBI Gene ID: | 83259 |
| NCBI Accession: | Q9BZA8.1 |
| UniProt Secondary Accession: | Q9BZA8,Q70LR6, Q70LR8, Q70LS0, Q70LS1, Q70LS2, Q70LS3 Q70LS4, Q70LS5, Q8WY34 |
| UniProt Related Accession: | Q9BZA8 |
| Molecular Weight: | 116,406 Da |
| NCBI Full Name: | Protocadherin-11 Y-linked |
| NCBI Synonym Full Names: | protocadherin 11 Y-linked |
| NCBI Official Symbol: | PCDH11Y |
| NCBI Official Synonym Symbols: | PCDHX; PCDHY; PCDH22; PCDH-PC |
| NCBI Protein Information: | protocadherin-11 Y-linked |
| UniProt Protein Name: | Protocadherin-11 Y-linked |
| UniProt Synonym Protein Names: | Protocadherin on the Y chromosome; PCDH-Y; Protocadherin prostate cancer; Protocadherin-PC; Protocadherin-22 |
| Protein Family: | Protocadherin |
| UniProt Gene Name: | PCDH11Y |
| UniProt Entry Name: | PC11Y_HUMAN |
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