Description
Product Name: | PCCB Monoclonal Antibody |
Product Code: | CAB24917 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC64902 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
Recommended Dilution: | WB 1:2000-1:7000, IHC-P 1:50-1:200, IF/ICC 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | 293T |
Cellular Location: | Mitochondrion matrix |
The protein encoded by this gene is a subunit of the propionyl-CoA carboxylase (PCC) enzyme, which is involved in the catabolism of propionyl-CoA. PCC is a mitochondrial enzyme that probably acts as a dodecamer of six alpha subunits and six beta subunits. This gene encodes the beta subunit of PCC. Defects in this gene are a cause of propionic acidemia type II (PA-2). Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 260-539 of Human PCCB(NP_000523.2). |
Sequence: | AFEND VDALC NLRDF FNYLP LSSQD PAPVR ECHDP SDRLV PELDT IVPLE STKAY NMVDI IHSVV DEREF FEIMP NYAKN IIVGF ARMNG RTVGI VGNQP KVASG CLDIN SSVKG ARFVR FCDAF NIPLI TFVDV PGFLP GTAQE YGGII RHGAK LLYAF AEATV PKVTV ITRKA YGGAY DVMSS KHLCG DTNYA WPTAE IAVMG AKGAV EIIFK GHENV EAAQA EYIEK FANPF PAAVR GFVDD IIQPS STRAR ICCDL DVLAS KKVQR PWRKH ANIPL |
Synonyms: | PCCB |
Calculated MW: | 58kDa |
Observed MW: | 58kDa |