PCBP4 Antibody (PACO19996)
- SKU:
- PACO19996
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | PCBP4 Antibody (PACO19996) |
| Antibody SKU: | PACO19996 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide of human PCBP4 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse kidney tissue, Primary antibody: PACO19996(PCBP4 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes. |
| Background: | This gene encodes a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. This gene is induced by the p53 tumor suppressor, and the encoded protein can suppress cell proliferation by inducing apoptosis and cell cycle arrest in G(2)-M. This gene's protein is found in the cytoplasm, yet it lacks the nuclear localization signals found in other subfamily members. Multiple alternatively spliced transcript variants have been described, but the full-length nature for only some has been determined. |
| Synonyms: | poly(rC) binding protein 4 |
| UniProt Protein Function: | PCBP4: Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 3p21Cellular Component: cytoplasm; ribonucleoprotein complexMolecular Function: DNA binding; RNA binding |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. This gene is induced by the p53 tumor suppressor, and the encoded protein can suppress cell proliferation by inducing apoptosis and cell cycle arrest in G(2)-M. This gene's protein is found in the cytoplasm, yet it lacks the nuclear localization signals found in other subfamily members. Multiple alternatively spliced transcript variants have been described, but the full-length nature for only some has been determined. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P57723 |
| NCBI GenInfo Identifier: | 224589815 |
| NCBI Gene ID: | 57060 |
| NCBI Accession: | NC_000003.11 |
| UniProt Secondary Accession: | P57723,Q96AH7 |
| UniProt Related Accession: | P57723 |
| Molecular Weight: | 37,078 Da |
| NCBI Full Name: | Homo sapiens chromosome 3, GRCh37.p13 Primary Assembly |
| NCBI Synonym Full Names: | poly(rC) binding protein 4 |
| NCBI Official Symbol: | PCBP4 |
| NCBI Official Synonym Symbols: | CBP; LIP4; MCG10 |
| NCBI Protein Information: | poly(rC)-binding protein 4; poly(rC)-binding protein 4; alpha-CP4; LYST-interacting protein; RNA binding protein MCG10 |
| UniProt Protein Name: | Poly(rC)-binding protein 4 |
| UniProt Synonym Protein Names: | Alpha-CP4 |
| Protein Family: | Poly(rC)-binding protein |
| UniProt Gene Name: | PCBP4 |
| UniProt Entry Name: | PCBP4_HUMAN |
| Antibodies |
| PCBP4 Antibody (PACO11091) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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