Description
system_update_alt Datasheet
| Product Name: | PCBP1 Antibody |
| Product Sku: | CPAB0595 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human PCBP1 mAb, clone PAT2A1AT, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PCBP1 protein 1-163 amino acids purified from Ecoli. |
| Clone: | PAT2A10AT. |
| Reactivity: | Other bodies |
| Applications: | Western Blot, ELISA |
| Purification Method: | PCBP1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
| Isotype: | IgG2a |
| Background: | PCBP1 is a single-stranded nucleic acid binding protein that binds preferentially to oligo dC. PCBP1 plays a role in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. PCBP1 along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. PCBP1 and PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promotes poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. |
| Synonyms: | Poly(rC) binding protein 1, hnRNP-E1, hnRNP-X, HNRPE1, HNRPX, Alpha-CP1, Heterogeneous nuclear ribonucleoprotein E1, Nucleic acid-binding protein SUB2.3, PCBP1. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |