Description
system_update_alt Datasheet
Product Name: | PCBP1 Antibody |
Product Sku: | CPAB0595 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human PCBP1 mAb, clone PAT2A1AT, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PCBP1 protein 1-163 amino acids purified from Ecoli. |
Clone: | PAT2A10AT. |
Reactivity: | Other bodies |
Applications: | Western Blot, ELISA |
Purification Method: | PCBP1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
Isotype: | IgG2a |
Background: | PCBP1 is a single-stranded nucleic acid binding protein that binds preferentially to oligo dC. PCBP1 plays a role in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. PCBP1 along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. PCBP1 and PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promotes poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. |
Synonyms: | Poly(rC) binding protein 1, hnRNP-E1, hnRNP-X, HNRPE1, HNRPX, Alpha-CP1, Heterogeneous nuclear ribonucleoprotein E1, Nucleic acid-binding protein SUB2.3, PCBP1. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |