PAX3 Monoclonal Antibody
- SKU:
- CAB22293
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | PAX3 Monoclonal Antibody |
| Product Code: | CAB22293 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC57259 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | 293T, U-251MG, Mouse brain, Rat brain |
| Cellular Location: | Nucleus |
This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 350-450 of human PAX3 (NP_852122.1). |
| Sequence: | SSSAY CLPST RHGFS SYTDS FVPPS GPSNP MNPTI GNGLS PQVMG LLTNH GGVPH QPQTD YALSP LTGGL EPTTT VSASC SQRLD HMKSL DSLPT SQSYC P |
| Synonyms: | WS1, WS3, CDHS, HUP2, PAX-3 |
| Calculated MW: | 53kDa |
| Observed MW: | 53kDa |
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