PASD1 Antibody (PACO37834)
- SKU:
- PACO37834
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | PASD1 Antibody (PACO37834) |
| Antibody SKU: | PACO37834 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Circadian clock protein PASD1 protein (301-600AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: PASD1 antibody at 4µg/ml + A549 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 88, 73 kDa. Observed band size: 88 kDa. |
| Background: | Functions as a suppressor of the biological clock that drives the daily circadian rhythms of cells throughout the body. Acts as a nuclear repressor of the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock components. Inhibits circadian clock function in cancer cells, when overexpressed. |
| Synonyms: | Circadian clock protein PASD1 (Cancer/testis antigen 63) (CT63) (OX-TES-1) (PAS domain-containing protein 1), PASD1 |
| UniProt Protein Function: | PASD1: May function as a transcription factor. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Cancer Testis Antigen (CTA)Chromosomal Location of Human Ortholog: Xq28Cellular Component: nucleoplasm; nucleusBiological Process: negative regulation of circadian rhythm; negative regulation of transcription, DNA-dependent |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a protein that is thought to function as a transcription factor. The protein is a cancer-associated antigen that can stimulate autologous T-cell responses, and it is therefore considered to be a potential immunotherapeutic target for the treatment of various hematopoietic malignancies, including diffuse large B-cell lymphoma. [provided by RefSeq, May 2010] |
| UniProt Code: | Q8IV76 |
| NCBI GenInfo Identifier: | 74728046 |
| NCBI Gene ID: | 139135 |
| NCBI Accession: | Q8IV76.1 |
| UniProt Secondary Accession: | Q8IV76,Q3MNE0, Q69HD7, Q8N7X9 |
| UniProt Related Accession: | Q8IV76 |
| Molecular Weight: | 72,738 Da |
| NCBI Full Name: | Circadian clock protein PASD1 |
| NCBI Synonym Full Names: | PAS domain containing 1 |
| NCBI Official Symbol: | PASD1 |
| NCBI Official Synonym Symbols: | CT63; OXTES1 |
| NCBI Protein Information: | circadian clock protein PASD1 |
| UniProt Protein Name: | Circadian clock protein PASD1 |
| UniProt Synonym Protein Names: | Cancer/testis antigen 63 |
| Protein Family: | Circadian clock protein |
| UniProt Gene Name: | PASD1 |
| UniProt Entry Name: | PASD1_HUMAN |
Related Products
HS3ST3B1 Antibody
Overview Product Name:HS3ST3B1 AntibodyProduct Code:PACO64781Size:50µLTarget Names:HS3ST3B1Species Reactivity:Human<
hns Antibody
Overview Product Name:hns AntibodyProduct Code:PACO64777Size:50µLTarget Names:hnsSpecies Reactivity:Escherichia coli
Avpr1b Antibody
Overview Product Name:Avpr1b AntibodyProduct Code:PACO64609Size:50µLTarget Names:Avpr1bSpecies Reactivity:RatHos
SIM1 Antibody
Overview Product Name:SIM1 AntibodyProduct Code:PACO64949Size:50µLTarget Names:SIM1Species Reactivity:HumanHost
eutC Antibody
Overview Product Name:eutC AntibodyProduct Code:PACO64709Size:50µLTarget Names:eutCSpecies Reactivity:Escherichia coli