Description
| Product Name: | PARVA Polyclonal Antibody |
| Product Code: | CAB24474 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | MCF7, HT-29 |
This gene encodes a member of the parvin family of actin-binding proteins. Parvins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. The encoded protein is part of the integrin-linked kinase signaling complex and plays a role in cell adhesion, motility and survival.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PARVA (NP_060692.3) . |
| Sequence: | MATSP QKSPS VPKSP TPKSP PSRKK DDSFL GKLGG TLARR KKAKE VSELQ EEGMN AINLP LSPIP FELDP EDTML EENEV RTMVD PNSRS DPKLQ ELMKV |
| Synonyms: | PARVA, CH-ILKBP, MXRA2, alpha-parvin |
| Calculated MW: | 20kDa/42kDa |
| Observed MW: | 45-50kDa |