PARP14 Antibody (PACO54510)
- SKU:
- PACO54510
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | PARP14 Antibody (PACO54510) |
| Antibody SKU: | PACO54510 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Poly [ADP-ribose] polymerase 14 protein (1600-1712AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescent analysis of HepG2 cells using PACO54510 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Enhances STAT6-dependent transcription (By similarity). Has ADP-ribosyltransferase activity. |
| Synonyms: | Poly [ADP-ribose] polymerase 14 (PARP-14) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (B aggressive lymphoma protein 2), PARP14, BAL2 KIAA1268 |
| UniProt Protein Function: | PARP14: Enhances STAT6-dependent transcription. Has ADP-ribosyltransferase activity. 5 isoforms of the human protein are produced by alternative splicing.Protein type: EC 2.4.2.30; Transcription, coactivator/corepressor; TransferaseChromosomal Location of Human Ortholog: 3q21.1Cellular Component: cytoplasm; cytosol; membrane; nucleusMolecular Function: enzyme binding; NAD+ ADP-ribosyltransferase activity; protein binding; RNA bindingBiological Process: innate immune response; negative regulation of gene expression; negative regulation of tyrosine phosphorylation of STAT protein; positive regulation of interleukin-4-mediated signaling pathway; positive regulation of tyrosine phosphorylation of STAT protein; protein ADP-ribosylation; regulation of transcription, DNA-templated; transcription, DNA-dependent |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the poly(ADP-ribose) polymerase (PARP) protein family. The encoded anti-apoptotic protein may regulate aerobic glycolysis and promote survival of cancer cells. Increased expression of this gene has been reported in a variety of tumor types. [provided by RefSeq, Jul 2016] |
| UniProt Code: | Q460N5 |
| NCBI GenInfo Identifier: | 154813199 |
| NCBI Gene ID: | 54625 |
| NCBI Accession: | NP_060024.2 |
| UniProt Secondary Accession: | Q460N5 |
| UniProt Related Accession: | Q460N5 |
| Molecular Weight: | |
| NCBI Full Name: | protein mono-ADP-ribosyltransferase PARP14 |
| NCBI Synonym Full Names: | poly(ADP-ribose) polymerase family member 14 |
| NCBI Official Symbol: | PARP14 |
| NCBI Official Synonym Symbols: | BAL2; ARTD8; pART8; PARP-14 |
| NCBI Protein Information: | protein mono-ADP-ribosyltransferase PARP14; poly [ADP-ribose] polymerase 14 |
| UniProt Protein Name: | Poly [ADP-ribose] polymerase 14 |
| UniProt Synonym Protein Names: | ADP-ribosyltransferase diphtheria toxin-like 8; ARTD8; B aggressive lymphoma protein 2 |
| Protein Family: | |
| UniProt Gene Name: | PARP14 |
| UniProt Entry Name: |
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