PARP11 Antibody (PACO16842)
- SKU:
- PACO16842
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | PARP11 Antibody (PACO16842) |
| Antibody SKU: | PACO16842 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Fusion protein of human PARP11 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO16842(PARP11 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO16842(PARP11 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | Poly(ADP-ribosylation) is a method of DNA damage-dependent posttranslational modification that helps to rescue injured proliferating cells from cell death. The PARP (poly(ADP-ribose) polymerase) proteins comprise a superfamily of enzymes that functionally modify histones and other nuclear proteins, thereby preventing cell death. PARPs use NAD+ as a substrate to catalytically transfer ADP-ribose residues onto protein acceptors; a process that, when repeated multiple times, leads to the formation of poly(ADPribose) chains on the protein. |
| Synonyms: | poly (ADP-ribose) polymerase family, member 11 |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9NR21 |
| NCBI GenInfo Identifier: | 194328777 |
| NCBI Gene ID: | 57097 |
| NCBI Accession: | NP_065100 |
| UniProt Secondary Accession: | Q9NR21 |
| UniProt Related Accession: | Q9NR21 |
| Molecular Weight: | |
| NCBI Full Name: | protein mono-ADP-ribosyltransferase PARP11 isoform a |
| NCBI Synonym Full Names: | poly(ADP-ribose) polymerase family member 11 |
| NCBI Official Symbol: | PARP11 |
| NCBI Official Synonym Symbols: | ARTD11; MIB006; C12orf6 |
| NCBI Protein Information: | protein mono-ADP-ribosyltransferase PARP11; poly [ADP-ribose] polymerase 11 |
| UniProt Protein Name: | Poly [ADP-ribose] polymerase 11 |
| UniProt Synonym Protein Names: | ADP-ribosyltransferase diphtheria toxin-like 11; ARTD11 |
| Protein Family: | |
| UniProt Gene Name: | PARP11 |
| UniProt Entry Name: | PAR11_HUMAN |
| Antibodies |
| PARP11 Antibody (PACO11074) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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