Description
Product Name: | PARG Monoclonal Antibody |
Product Code: | CAB24811 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC63810 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:1000-1:5000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | PC-3 |
Cellular Location: | Cytoplasm, Mitochondrion, Mitochondrion matrix, Nucleus |
Poly(ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly(ADP-ribose), a reversible covalent-modifier of chromosomal proteins. The protein is found in many tissues and may be subject to proteolysis generating smaller, active products. Several transcript variants encoding different isoforms have been found for this gene.
Immunogen: | Recombinant Protein corresponding to a sequence within amino acids 777-976 of human PARG(NP_003622.2). |
Sequence: | HNECL IITGT EQYSE YTGYA ETYRW SRSHE DGSER DDWQR RCTEI VAIDA LHFRR YLDQF VPEKM RRELN KAYCG FLRPG VSSEN LSAVA TGNWG CGAFG GDARL KALIQ ILAAA AAERD VVYFT FGDSE LMRDI YSMHI FLTER KLTVG DVYKL LLRYY NEECR NCSTP GPDIK LYPFI YHAVE SCAET ADHSG QRTGT |
Synonyms: | PARG99 |
Calculated MW: | 111kDa |
Observed MW: | 120-130kDa |