Description
Product Name: | Papillary renal cell carcinoma Polyclonal Antibody |
Product Code: | CAB18781 |
Reactivity: | Human |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:1000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
Positive Samples: | HeLa |
Cellular Location: | nuclear speck, nucleoplasm, nucleus |
This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1)(p11;q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle.
Immunogen: | A synthetic peptide of Human Papillary renal cell carcinoma. |
Sequence: | Email for sequence |
Synonyms: | TPRC, RCCP1 |
Calculated MW: | 52kDa |
Observed MW: | 66kDa |