Antibody Name:	Paox Antibody (PACO37582)
Antibody SKU:	PACO37582
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA
Recommended Dilutions:
Species Reactivity:	Mouse
Immunogen:	Recombinant Mouse Peroxisomal N(1)-acetyl-spermine/spermidine oxidase protein (1-504AA)

Form:	Liquid
Storage Buffer:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:	>95%, Protein G purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

Background:

Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs.

Synonyms:

Peroxisomal N(1)-acetyl-spermine/spermidine oxidase (EC 1.5.3.13) (Polyamine oxidase), Paox, Pao

UniProt Protein Function:	PAOX: Flavoenzyme which catalyzes the oxidation of N(1)- acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)- acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. Belongs to the flavin monoamine oxidase family. 11 isoforms of the human protein are produced by alternative splicing.Protein type: EC 1.5.3.13; OxidoreductaseChromosomal Location of Human Ortholog: 7\|7 F4Cellular Component: cytoplasm; peroxisomal matrix; peroxisomeMolecular Function: oxidoreductase activity; polyamine oxidase activity; receptor bindingBiological Process: polyamine catabolic process; putrescine biosynthetic process; putrescine catabolic process; spermidine catabolic process; spermine catabolic process
UniProt Protein Details:
NCBI Summary:
UniProt Code:	Q8C0L6
NCBI GenInfo Identifier:	28173566
NCBI Gene ID:	212503
NCBI Accession:	NP_722478.2
UniProt Secondary Accession:	Q8C0L6,Q8K254
UniProt Related Accession:	Q8C0L6
Molecular Weight:
NCBI Full Name:	peroxisomal N(1)-acetyl-spermine/spermidine oxidase isoform 1
NCBI Synonym Full Names:	polyamine oxidase (exo-N4-amino)
NCBI Official Symbol:	Paox
NCBI Official Synonym Symbols:	Pao; AI118225; 2410012F02Rik
NCBI Protein Information:	peroxisomal N(1)-acetyl-spermine/spermidine oxidase
UniProt Protein Name:	Peroxisomal N(1)-acetyl-spermine/spermidine oxidase
UniProt Synonym Protein Names:	Polyamine oxidase
Protein Family:	Polyamine oxidase
UniProt Gene Name:	Paox
UniProt Entry Name: