Paox Antibody (PACO37582)
- SKU:
- PACO37582
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | Paox Antibody (PACO37582) |
| Antibody SKU: | PACO37582 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Mouse |
| Immunogen: | Recombinant Mouse Peroxisomal N(1)-acetyl-spermine/spermidine oxidase protein (1-504AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. |
| Synonyms: | Peroxisomal N(1)-acetyl-spermine/spermidine oxidase (EC 1.5.3.13) (Polyamine oxidase), Paox, Pao |
| UniProt Protein Function: | PAOX: Flavoenzyme which catalyzes the oxidation of N(1)- acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)- acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. Belongs to the flavin monoamine oxidase family. 11 isoforms of the human protein are produced by alternative splicing.Protein type: EC 1.5.3.13; OxidoreductaseChromosomal Location of Human Ortholog: 7|7 F4Cellular Component: cytoplasm; peroxisomal matrix; peroxisomeMolecular Function: oxidoreductase activity; polyamine oxidase activity; receptor bindingBiological Process: polyamine catabolic process; putrescine biosynthetic process; putrescine catabolic process; spermidine catabolic process; spermine catabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8C0L6 |
| NCBI GenInfo Identifier: | 28173566 |
| NCBI Gene ID: | 212503 |
| NCBI Accession: | NP_722478.2 |
| UniProt Secondary Accession: | Q8C0L6,Q8K254 |
| UniProt Related Accession: | Q8C0L6 |
| Molecular Weight: | |
| NCBI Full Name: | peroxisomal N(1)-acetyl-spermine/spermidine oxidase isoform 1 |
| NCBI Synonym Full Names: | polyamine oxidase (exo-N4-amino) |
| NCBI Official Symbol: | Paox |
| NCBI Official Synonym Symbols: | Pao; AI118225; 2410012F02Rik |
| NCBI Protein Information: | peroxisomal N(1)-acetyl-spermine/spermidine oxidase |
| UniProt Protein Name: | Peroxisomal N(1)-acetyl-spermine/spermidine oxidase |
| UniProt Synonym Protein Names: | Polyamine oxidase |
| Protein Family: | Polyamine oxidase |
| UniProt Gene Name: | Paox |
| UniProt Entry Name: |
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