PAOX Antibody (PACO01816)
- SKU:
- PACO01816
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | PAOX Antibody |
| Antibody SKU: | PACO01816 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | WB:1:500-1:2000 |
| Species Reactivity: | Human |
| Immunogen: | synthesized peptide derived from the Internal region of human PAOX. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | PAOX; PAO; Peroxisomal N(1)-acetyl-spermine/spermidine oxidase; Polyamine oxidase |
| UniProt Protein Function: | PAOX: Flavoenzyme which catalyzes the oxidation of N(1)- acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)- acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. Belongs to the flavin monoamine oxidase family. 11 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 1.5.3.13; Oxidoreductase Chromosomal Location of Human Ortholog: 10q26.3 Cellular Component: peroxisomal matrix Molecular Function:polyamine oxidase activity; receptor binding Biological Process: spermine catabolic process; xenobiotic metabolic process; polyamine biosynthetic process; putrescine biosynthetic process; polyamine catabolic process; spermidine catabolic process; putrescine catabolic process; polyamine metabolic process |
| UniProt Code: | Q6QHF9 |
| NCBI GenInfo Identifier: | 51316248 |
| NCBI Gene ID: | 196743 |
| NCBI Accession: | Q6QHF9.3 |
| UniProt Secondary Accession: | Q6QHF9,Q5VWY0, Q6QHF5, Q6QHF6, Q6QHF7, Q6QHF8, Q6QHG0 Q6QHG1, Q6QHG2, Q6QHG3, Q6QHG4, D3DXI6, |
| UniProt Related Accession: | Q6QHF9 |
| Molecular Weight: | 649 |
| NCBI Full Name: | Peroxisomal N(1)-acetyl-spermine/spermidine oxidase |
| NCBI Synonym Full Names: | polyamine oxidase (exo-N4-amino) |
| NCBI Official Symbol: | PAOX |
| NCBI Official Synonym Symbols: | PAO |
| NCBI Protein Information: | peroxisomal N(1)-acetyl-spermine/spermidine oxidase; peroxisomal N(1)-acetyl-spermine/spermidine oxidase; peroxisomal N1-acetyl-spermine/spermidine oxidase |
| UniProt Protein Name: | Peroxisomal N(1)-acetyl-spermine/spermidine oxidase |
| UniProt Synonym Protein Names: | Polyamine oxidase |
| Protein Family: | Peroxisomal N(1)-acetyl-spermine/spermidine oxidase |
| UniProt Gene Name: | PAOX |
| UniProt Entry Name: | PAOX_HUMAN |
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