PANX3 Antibody (PACO59285)
- SKU:
- PACO59285
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | PANX3 Antibody (PACO59285) |
| Antibody SKU: | PACO59285 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Pannexin-3 protein (135-215AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: Hela whole cell lysate, HepG2 whole cell lysate. All lanes: PANX3 antibody at 4µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 45 kDa. Observed band size: 45 kDa. |
 | Immunofluorescence staining of HepG2 cells with PACO59285 at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Structural component of the gap junctions and the hemichannels. |
| Synonyms: | Pannexin-3, PANX3 |
| UniProt Protein Function: | PANX3: Structural component of the gap junctions and the hemichannels. Belongs to the pannexin family.Protein type: Membrane protein, integral; Cell adhesion; Membrane protein, multi-passChromosomal Location of Human Ortholog: 11q24.2Cellular Component: endomembrane system; plasma membraneMolecular Function: gap junction hemi-channel activity; wide pore channel activityBiological Process: cation transport; cell-cell signaling |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene belongs to the innexin family. Innexin family members are known to be the structural components of gap junctions. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q96QZ0 |
| NCBI GenInfo Identifier: | 20139071 |
| NCBI Gene ID: | 116337 |
| NCBI Accession: | Q96QZ0.1 |
| UniProt Secondary Accession: | Q96QZ0 |
| UniProt Related Accession: | Q96QZ0 |
| Molecular Weight: | 44,683 Da |
| NCBI Full Name: | Pannexin-3 |
| NCBI Synonym Full Names: | pannexin 3 |
| NCBI Official Symbol: | PANX3 |
| NCBI Official Synonym Symbols: | PX3 |
| NCBI Protein Information: | pannexin-3 |
| UniProt Protein Name: | Pannexin-3 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Pannexin |
| UniProt Gene Name: | PANX3 |
| UniProt Entry Name: | PANX3_HUMAN |
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