Pan Lactic acid-Lysine Monoclonal Antibody
- SKU:
- CAB23004
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | Pan Lactic acid-Lysine Monoclonal Antibody |
| Product Code: | CAB23004 |
| Reactivity: | Human, Mouse, Rat, Other (Wide Range) |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC59407 |
| Reactivity: | Human, Mouse, Rat, Other (Wide Range) |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | MCF7, NIH/3T3, C6 cells were treated by Sodium lactate |
Histone lysine lactation (Kla) is a newly discovered histone modification that regulates gene expression in macrophages. In M1 macrophages, lactic acid is derived from incompletely oxidized glucose and then produces lactyl-CoA, which is transferred via acetyltransferase p300 to the lysine tail of the histone. This modification is abundant in gene promoter regions that lack acetylation and are associated with gene expression activation.
| Immunogen: | A synthetic peptide corresponding to a sequence containing Pan Lactic acid-Lysine. |
| Sequence: | Email for sequence |
| Observed MW: | 15kDa-250kDa |
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