PAK2 Polyclonal Antibody
- SKU:
- CAB21522
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | PAK2 Polyclonal Antibody |
| Product Code: | CAB21522 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa |
| Cellular Location: | Cytoplasm, Cytoplasm, Lipid-anchor, Membrane, Nucleus, perinuclear region |
The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-212 of human PAK2 (NP_002568.2). |
| Sequence: | MSDNG ELEDK PPAPP VRMSS TIFST GGKDP LSANH SLKPL PSVPE EKKPR HKIIS IFSGT EKGSK KKEKE RPEIS PPSDF EHTIH VGFDA VTGEF TGMPE QWARL LQTSN ITKLE QKKNP QAVLD VLKFY DSNTV KQKYL SFTPP EKDGF PSGTP ALNAK GTEAP AVVTE EEDDD EETAP PVIAP RPDHT KSIYT RSVID PVPAP VGDSH VD |
| Synonyms: | KNO2, PAK65, PAKgamma |
| Calculated MW: | 58kDa |
| Observed MW: | 58kDa |
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