PAIP2 Monoclonal Antibody [PAT1C12AT] (CPAB0460)
![PAIP2 Monoclonal Antibody [PAT1C12AT] (CPAB0460)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/58682/63864/paip2-monoclonal-antibody-pat1c12at-cpab0460__67117__84896.1706535182.jpg?c=1 "PAIP2 Monoclonal Antibody [PAT1C12AT] (CPAB0460)")
- SKU:
- CPAB0460
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
- Host Species:
- Mouse
- Isotype:
- IgG2b
- Clone:
- PAT1C12AT
- Applications:
- WB
- Applications:
- ELISA
![PAIP2 Monoclonal Antibody [PAT1C12AT] (CPAB0460)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/58682/63864/paip2-monoclonal-antibody-pat1c12at-cpab0460__67117__84896.1706535182.jpg?c=1&imbypass=on "PAIP2 Monoclonal Antibody [PAT1C12AT] (CPAB0460)")
Description
system_update_alt Datasheet
| Product Name: | PAIP2 Antibody |
| Product Sku: | CPAB0460 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human PAIP2 mAb is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human CMBL 1-127 amino acids purified from Ecoli. |
| Clone: | PAT1C12AT. |
| Reactivity: | Other bodies |
| Applications: | Western Blot, ELISA |
| Purification Method: | PAIP2 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
| Isotype: | IgG2b |
| Background: | PAIP2 has a role as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. PAIP2 inhibitory activity on translation is mediated through its action on PABPC1. PAIP2 displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. PAIP2 association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization. |
| Synonyms: | Poly(A) Binding Protein Interacting Protein 2, PABP- interacting protein 2, HSPC218, PAIP-2, PAIP2A, Polyadenylate-binding protein-interacting protein 2, PAIP2, MGC72018. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
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