Description
Product Name: | P2RY11 Polyclonal Antibody |
Product Code: | CAB24482 |
Reactivity: | Human, Mouse |
Applications: | Immunofluorescence |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human, Mouse |
Tested Applications: | IF/ICC, ELISA |
Key Applications: | Immunofluorescence |
Recommended Dilution: | IF/ICC 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
Cellular Location: | Cell membrane, Multi-pass membrane protein |
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is coupled to the stimulation of the phosphoinositide and adenylyl cyclase pathways and behaves as a selective purinoceptor. Naturally occuring read-through transcripts, resulting from intergenic splicing between this gene and an immediately upstream gene (PPAN, encoding peter pan homolog), have been found. The PPAN-P2RY11 read-through mRNA is ubiquitously expressed and encodes a fusion protein that shares identity with each individual gene product.
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human P2RY11 (NP_002557.2). |
Sequence: | MAANV SGAKS CPANF LAAAD DKLSG FQGDF LWPIL VVEFL VAVAS NGLAL YRFSI RKQRP WHPAV VFSVQ LAVSD LLCAL TLPPL AAYLY PPKHW RYGEA |
Synonyms: | P2RY11, P2Y11, P2Y purinoceptor 11 |
Calculated MW: | 40kDa |
Observed MW: | Refer to figures |